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PARP1 抗体

This anti-PARP1 antibody is a 兔 多克隆 antibody detecting PARP1 in WB, ELISA 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5702300
发货至: 中国

Quick Overview for PARP1 抗体 (ABIN5702300)

抗原

See all PARP1 抗体
PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

适用

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人, 小鼠, 大鼠

宿主

  • 246
  • 29
  • 1

克隆类型

  • 200
  • 76
多克隆

标记

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This PARP1 antibody is un-conjugated

应用范围

  • 191
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Western Blotting (WB), ELISA, Immunoprecipitation (IP)
  • 原理

    PARP1 antibody

    免疫原

    poly (ADP-ribose) polymerase 1

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

    别名

    PARP1

    背景

    Synonyms: Poly [ADP-ribose] polymerase 1 (PARP-1)|ADP-ribosyltransferase diphtheria toxin-like 1 (ARTD1)|DNA ADP-ribosyltransferase PARP1|NAD(+) ADP-ribosyltransferase 1 (ADPRT 1)|Poly[ADP-ribose] synthase 1|Protein poly-ADP-ribosyltransferase PARP1|Poly [ADP-ribose] polymerase 1, processed C-terminus Alternative names: Poly [ADP-ribose] polymerase 1, 89- kDa form|Poly [ADP-ribose] polymerase 1, processed N-terminus (NT-PARP-1) Alternative names: Poly [ADP-ribose] polymerase 1, 24- kDa form|Poly [ADP-ribose] polymerase 1, 28- kDa form|PARP1|ADPRT|PPOL

    Background: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

    基因ID

    142

    UniProt

    P09874

    途径

    Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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